Time, or DOI:10.1038/s41586-020-2975-4 is a painting inspired by research by Prof. Sinclair’s team. The painting is part of a mini-series featuring famous rats experiments reinterpreted through art. The painting shows three generation of rats “united” by their epigenetic signature.
Sinclair and team are working to restore youthful epigenetic signatures to restore old tissues, and in a sense reverse time and aging. In the paper that inspired the painting, they show how inducing 3 genes (OSK) expression causes neurons in old mice to function as though they were young. Using the eye as a model tissue, they effectively promote in vivo epigenetic restoration of aged neurons.
|Art Height:||17.8 cm (7”)|
|Art Width:||12.6 cm (5”)|
|Frame Height:||26 cm (10”1/4)|
|Frame Width:||21 cm (8”3/8)|
|Medium:||Acrylic on gesso-ed paper|
|Features:||Hand-painted Rustic Up-cycled Frame